Description

2-(Chloromethyl)-Oxazolo[5,4-B]Pyridine is a high-value heterocyclic building block featuring a fused oxazole-pyridine core with a reactive chloromethyl side chain. This compound is of significant interest for its role in facilitating the synthesis of complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the heterocyclic structure can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to its reactive chloromethyl group, which can be used for bioconjugation.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	2-(Chloromethyl)-Oxazolo[5,4-B]Pyridine
CAS No.	1092352-10-7
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	2-(Chloromethyl)[1,3]oxazolo[5,4-b]pyridine; Oxazolo[5,4-b]pyridine, 2-(chloromethyl)-; 2-(Chloromethyl)oxazolo[5,4-b]pyridine; 2-Chloromethyloxazolo[5,4-b]pyridine; [1,3]Oxazolo[5,4-b]pyridine, 2-(chloromethyl)-; 1092352-10-7; 2-(Chloromethyl)-[1,3]oxazolo[5,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-Oxazolo[5,4-B]Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and stringent in-process controls guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; ensure containers are sealed under an inert atmosphere if specified for the grade.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.