Description

N'-(4-Methoxybenzoyl)-6-(Trifluoromethyl)Nicotinohydrazide is a high-purity, advanced pharmaceutical intermediate with the CAS number 1092346-04-7. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its nicotinohydrazide and trifluoromethyl motifs.
• Agrochemical Development: Serves as a building block for developing new crop protection agents and pesticides.
• Biochemical Tool Compound: Utilized in biochemical assays and as a probe for studying specific enzyme interactions or biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: Used in university laboratories for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	N'-(4-Methoxybenzoyl)-6-(Trifluoromethyl)Nicotinohydrazide
CAS No.	1092346-04-7
Molecular Formula	C15H12F3N3O3
Molecular Weight	339.27 g/mol
Synonyms	6-(Trifluoromethyl)-N'-(4-methoxybenzoyl)nicotinohydrazide; 2-Pyridinecarboxamide, N'-[(4-methoxyphenyl)carbonyl]-6-(trifluoromethyl)-; Nicotinohydrazide, N'-(4-methoxybenzoyl)-6-(trifluoromethyl)-; 6-Trifluoromethyl-N'-(p-anisoyl)nicotinohydrazide; p-Anisoyl hydrazide of 6-trifluoromethylnicotinic acid; 1092346-04-7; N'-(4-Methoxybenzoyl)-6-(trifluoromethyl)pyridine-3-carbohydrazide
EINECS	Contact for details

Quality Control

Our N'-(4-Methoxybenzoyl)-6-(Trifluoromethyl)Nicotinohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.