Description

4-Bromo-3-Methyl-Isoxazole-5-Carboxylic Acid Methyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive bromine and ester functional groups, which enable efficient derivatization and incorporation into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating libraries of bioactive heterocycles.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging the isoxazole ring's bioactivity.
• Chemical Research: Serves as a versatile building block in academic and industrial laboratories for method development and novel compound synthesis.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or ligands with unique electronic properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination.

Basic Information

Product Name	4-Bromo-3-Methyl-Isoxazole-5-Carboxylic Acid Methyl Ester
CAS No.	1092301-44-4
Molecular Formula	C7H8BrNO3
Molecular Weight	234.05 g/mol
Synonyms	Methyl 4-bromo-3-methyl-1,2-oxazole-5-carboxylate; 4-Bromo-3-methylisoxazole-5-carboxylic acid methyl ester; 5-Carbomethoxy-4-bromo-3-methylisoxazole; 1,2-Oxazole-5-carboxylic acid, 4-bromo-3-methyl-, methyl ester; 4-Bromo-3-methyl-isoxazol-5-carbonsaeure-methylester
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Methyl-Isoxazole-5-Carboxylic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.