Description

5-Iodo-2-Methylnicotinic Acid is a halogenated nicotinic acid derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its core value proposition lies in its unique molecular structure, which combines a reactive iodine substituent with the methylnicotinic acid scaffold, enabling precise chemical modifications. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders or as enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators where the iodine atom facilitates further functionalization.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Advanced Material Development: Acts as a monomer or functional unit in the creation of specialized polymers or organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl or other complex structures.

Basic Information

Product Name	5-Iodo-2-Methylnicotinic Acid
CAS No.	1092286-33-3
Molecular Formula	C7H6INO2
Molecular Weight	263.03 g/mol
Synonyms	2-Methyl-5-iodonicotinic Acid; 5-Iodo-2-methylpyridine-3-carboxylic Acid; 3-Carboxy-5-iodo-2-methylpyridine; 2-Methyl-5-iodo-3-pyridinecarboxylic Acid; 1092286-33-3; 5-Iodo-2-methyl-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-Methylnicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.