Description

2-Chloropyridine is a versatile halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, enabling precise molecular modifications. Industries such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical production rely on high-purity 2-chloropyridine CAS NO 1092171-93-1 for its reliable reactivity and selectivity in cross-coupling and substitution reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in manufacturing herbicides, fungicides, and insecticides, where the chloropyridine moiety contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Functional Material Development: Employed in the research and production of electronic chemicals, liquid crystals, and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: Acts as a pivotal substrate in Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl and heterobiaryl structures.
• Nucleophilic Substitution: The chlorine atom is readily displaced by various nucleophiles (amines, alkoxides) to create diverse pyridine derivatives.

Basic Information

Product Name	2-Chloropyridine
CAS No.	1092171-93-1
Molecular Formula	C5H4ClN
Molecular Weight	113.54 g/mol
Synonyms	2-Chloropyridine; α-Chloropyridine; o-Chloropyridine; Pyridine, 2-chloro-; 2-Pyridyl chloride; NSC 8755; 2-Cl-Py
EINECS	Contact for details

Quality Control

Our 2-Chloropyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its organic and halogenated nature, store separately from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.