Description

2-Chloro-5-Cyanonicotinic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value proposition lies in its unique molecular architecture, which combines a reactive pyridine core with both chloro and cyano substituents, enabling precise derivatization for creating complex target molecules. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine scaffold.
• Ligand and Catalyst Development: Serves as a versatile starting material for constructing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of organic electronic materials and functional polymers due to its electron-withdrawing groups.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses (CDMOs) producing bespoke compounds for client R&D programs.
• Academic & Institutional Research: Used in university and government labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Chloro-5-Cyanonicotinic Acid
CAS No.	1089335-56-7
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	5-Cyano-2-chloropyridine-3-carboxylic acid; 2-Chloro-5-cyanopyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-chloro-5-cyano-; 2-Chloro-5-cyano-nicotinic acid; 1089335-56-7; 2-Chloro-5-cyanonicotinic acid; Nicotinic acid, 2-chloro-5-cyano-
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Cyanonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.