Description

Ethyl 6-(Bis-tert-Butoxycarbonyl)Aminonicotinat is a high-purity, protected nicotinic acid derivative, specifically designed as a critical building block in advanced organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing nicotinamide or pyridine-based pharmacophores.
• Peptide Mimetics & PROTACs: Serves as a versatile linker or core structure in the design of peptide mimetics and Proteolysis Targeting Chimeras (PROTACs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that utilize nicotinic acid derivatives.
• Ligand & Catalyst Development: Employed as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers and functional materials.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory chemistry and method development.

Basic Information

Product Name	Ethyl 6-(Bis-tert-Butoxycarbonyl)Aminonicotinat
CAS No.	1089330-72-2
Molecular Formula	C19H28N2O6
Molecular Weight	380.44 g/mol
Synonyms	Ethyl 6-[(bis(tert-butoxycarbonyl)amino)]nicotinate; 6-[(Di-tert-butoxycarbonyl)amino]nicotinic Acid Ethyl Ester; Ethyl 6-((Boc)2Amino)nicotinate; 2,5-Pyridinedicarboxylic Acid, 6-[(Bis[(1,1-Dimethylethoxy)carbonyl]Amino]-, 5-Ethyl Ester; Ethyl 6-(Di-Boc-amino)nicotinate; 6-(N,N-Di-Boc-amino)nicotinic Acid Ethyl Ester; Aminonicotinic Acid Ethyl Ester Boc-Protected Derivative
EINECS	Contact for details

Quality Control

Our Ethyl 6-(Bis-tert-Butoxycarbonyl)Aminonicotinat is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, such as cGMP development and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.