Description

4-(6-(Piperazin-1-Yl)-4-(Trifluoromethyl)Pyridin-2-Yl)Morpholine is a high-value, heterocyclic organic compound featuring a pyridine core substituted with both morpholine and piperazine moieties, as well as a trifluoromethyl group. This unique structure makes it a critical pharmaceutical intermediate for the synthesis of advanced active ingredients, particularly in drug discovery programs targeting central nervous system (CNS) disorders and oncology. It is primarily sought by research institutions, CROs, and pharmaceutical manufacturers engaged in the development of novel small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially for CNS-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its privileged heterocyclic scaffold.
• Kinase Inhibitor Development: Serves as a core fragment in the design and production of potential kinase inhibitors for cancer treatment.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein functions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CRAMOs) producing specialized compounds for clients.
• Agrochemical Research: Potential intermediate in the discovery of new active ingredients for crop protection products.

Basic Information

Product Name	4-(6-(Piperazin-1-Yl)-4-(Trifluoromethyl)Pyridin-2-Yl)Morpholine
CAS No.	1089330-41-5
Molecular Formula	C14H19F3N4O
Molecular Weight	316.33 g/mol
Synonyms	4-[6-(Piperazin-1-yl)-4-(trifluoromethyl)pyridin-2-yl]morpholine; 2-Morpholino-6-(piperazin-1-yl)-4-(trifluoromethyl)pyridine; 1089330-41-5; 4-(6-Piperazin-1-yl-4-trifluoromethylpyridin-2-yl)morpholine; 4-(6-(1-Piperazinyl)-4-(trifluoromethyl)-2-pyridinyl)morpholine
EINECS	Contact for details

Quality Control

Our 4-(6-(Piperazin-1-Yl)-4-(Trifluoromethyl)Pyridin-2-Yl)Morpholine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.