Description

3-(5,6-Dimethoxypyridin-2-Yl)Prop-2-Yn-1-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine and alkyne functional groups. This compound matters as a critical building block for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily needed by research institutions and pharmaceutical companies developing novel therapeutics, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for oncology and CNS targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries via click chemistry and other alkyne-based coupling reactions.
• Kinase Inhibitor Synthesis: Serves as a core structural component in the preparation of potent and selective kinase inhibitors.
• Bioconjugation: The terminal alkyne group enables its use in bioorthogonal labeling and probe development for biochemical assays.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science: Can be utilized in the synthesis of specialized ligands for catalysts or functional organic materials.

Basic Information

Product Name	3-(5,6-Dimethoxypyridin-2-Yl)Prop-2-Yn-1-Ol
CAS No.	1087659-28-6
Molecular Formula	C₁₀H₁₁NO₃
Molecular Weight	193.20 g/mol
Synonyms	2-(3-Hydroxyprop-1-yn-1-yl)-5,6-dimethoxypyridine; 5,6-Dimethoxy-2-(3-hydroxy-1-propynyl)pyridine; 3-(5,6-Dimethoxy-2-pyridinyl)-2-propyn-1-ol; 2-Propyne-1-ol, 3-(5,6-dimethoxy-2-pyridinyl)-; 1087659-28-6
EINECS	Contact for details

Quality Control

Our 3-(5,6-Dimethoxypyridin-2-Yl)Prop-2-Yn-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.