Description

5-Bromo-3-Methoxy-2-((Trimethylsilyl)Ethynyl)-Pyridine is a high-value, multi-functional pyridine derivative designed for advanced synthetic chemistry. This compound serves as a critical key intermediate and versatile building block in the development of complex molecules. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel crop protection agents, including herbicides and fungicides.
• Material Science Precursor: Serves as a monomer or ligand precursor in the development of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The bromo and ethynyl groups make it an excellent substrate for Sonogashira, Suzuki, and other palladium-catalyzed cross-coupling reactions.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Ligand Synthesis: Used to prepare sophisticated ligands for catalysis and coordination chemistry.

Basic Information

Item	Details
Product Name	5-Bromo-3-Methoxy-2-((Trimethylsilyl)Ethynyl)-Pyridine
CAS No.	1087659-23-1
Molecular Formula	C11H14BrNOSi
Molecular Weight	284.23 g/mol
Synonyms	2-[(Trimethylsilyl)ethynyl]-5-bromo-3-methoxypyridine; 5-Bromo-3-methoxy-2-((trimethylsilyl)ethynyl)pyridine; 5-Bromo-3-methoxy-2-(2-trimethylsilylethynyl)pyridine; 2-(Trimethylsilylethynyl)-5-bromo-3-methoxypyridine; Pyridine, 5-bromo-3-methoxy-2-[(trimethylsilyl)ethynyl]-; 1087659-23-1
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Methoxy-2-((Trimethylsilyl)Ethynyl)-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.