Description

8-Cbz-1,8-Diazaspiro[5.5]Undecane is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly within central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent and selective receptor modulators and enzyme inhibitors.
• Drug Discovery & Medicinal Chemistry: Serves as a versatile scaffold for constructing spirocyclic compounds to explore new chemical space and improve drug-like properties such as metabolic stability and solubility.
• CNS-Active Compound Synthesis: Used in the research and development of potential treatments for neurological disorders.
• Oncological Research: Employed in creating novel chemical entities for targeted cancer therapy development.
• Chemical Biology Probes: Acts as a core structure for developing tool compounds to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Supplied for route scouting and optimization during the transition from laboratory to pilot-scale production.

Basic Information

Product Name	8-Cbz-1,8-Diazaspiro[5.5]Undecane
CAS No.	1086394-89-9
Molecular Formula	C19H26N2O2
Molecular Weight	314.43 g/mol
Synonyms	1,8-Diazaspiro[5.5]undecane, 8-[(phenylmethoxy)carbonyl]-; 8-[(Benzyloxy)carbonyl]-1,8-diazaspiro[5.5]undecane; 8-Cbz-1,8-Diazaspiro[5.5]undecane; Carbobenzyloxy-Protected 1,8-Diazaspiro[5.5]undecane; Cbz-Protected Spirocyclic Diamine; 1,8-Diazaspiro[5.5]undecane-8-carboxylic acid benzyl ester; 8-N-Cbz-1,8-Diazaspiro[5.5]undecane
EINECS	Contact for details

Quality Control

Our 8-Cbz-1,8-Diazaspiro[5.5]Undecane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.