Description

Benzyl 2,6-Diazaspiro[3.4]Octane-2-Carboxylate is a high-value, spirocyclic building block and intermediate in advanced organic synthesis. Its unique constrained diazaspiro structure makes it a critical scaffold for medicinal chemistry research, particularly in the development of novel therapeutic agents. This compound is essential for pharmaceutical R&D teams and fine chemical manufacturers focused on creating innovative small molecule drugs targeting central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in protease inhibitor and receptor modulator programs.
• Medicinal Chemistry Research: Used as a privileged scaffold to explore structure-activity relationships (SAR) and improve pharmacokinetic properties like solubility and metabolic stability.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds and probes to study biological pathways and target validation.
• Agrochemical Research: Potential intermediate in the discovery of new active ingredients with novel modes of action.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring complex nitrogen-containing heterocycles.

Basic Information

Product Name	Benzyl 2,6-Diazaspiro[3.4]Octane-2-Carboxylate
CAS No.	1086394-87-7
Molecular Formula	C14H18N2O2
Molecular Weight	246.31 g/mol
Synonyms	2,6-Diazaspiro[3.4]octane-2-carboxylic acid benzyl ester; Benzyl 2,6-diazaspiro[3.4]octane-2-carboxylate; 2,6-Diazaspiro[3.4]octane-2-carboxylic acid, phenylmethyl ester; 1086394-87-7; UNII-8K3B8U2Q4F; Spiro[3.4]octane-2,6-diazine-2-carboxylic acid benzyl ester; Benzyl ester of 2,6-diazaspiro[3.4]octane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Benzyl 2,6-Diazaspiro[3.4]Octane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.