Description

2-Cbz-2,8-Diazaspiro[5.5]Undecane is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic diaza scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex molecules for drug discovery and development programs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• CNS Drug Development: Its structural features make it particularly relevant for creating potential therapeutics for neurological and psychiatric conditions.
• Proteolysis Targeting Chimera (PROTAC) Synthesis: Can be utilized as a linker or component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Employed in the development of tool compounds to study biological pathways and protein function.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	2-Cbz-2,8-Diazaspiro[5.5]Undecane
CAS No.	1086394-63-9
Molecular Formula	C17H24N2O2
Molecular Weight	288.39 g/mol
Synonyms	Carbobenzyloxy-2,8-diazaspiro[5.5]undecane; 2,8-Diazaspiro[5.5]undecane, 2-[(phenylmethoxy)carbonyl]-; 2-(Benzyloxycarbonyl)-2,8-diazaspiro[5.5]undecane; 2-Cbz-2,8-Diazaspiro[5.5]undecane; 2,8-Diazaspiro[5.5]undecane-2-carboxylic acid benzyl ester; 2-N-Cbz-2,8-Diazaspiro[5.5]undecane; 2-(Benzyloxycarbonyl)-2,8-diazaspiro[5.5]undecane; 2-Cbz-2,8-Diazaspiro[5.5]Undecane Hydrochloride (salt forms may exist)
EINECS	Contact for details

Quality Control

Our 2-Cbz-2,8-Diazaspiro[5.5]Undecane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.