Description

2,6-Diazaspiro[4.5]Decane-2-Carboxylic Acid, 1,1-Dimethylethyl Ester is a high-value, protected spirocyclic building block essential for modern organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceuticals, particularly for creating complex molecular architectures with specific three-dimensional properties. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate constrained, nitrogen-rich scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Protease Inhibitor Scaffold: Used in the research and development of novel protease inhibitors due to its constrained spirocyclic structure.
• Agrochemical Research: Serves as a precursor for developing new active ingredients with enhanced biological activity and selectivity.
• Ligand Synthesis: Employed in medicinal chemistry for constructing complex ligands for various biological targets and receptors.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and protein-protein interactions.
• Peptidomimetics: Integral for designing and synthesizing peptidomimetic compounds that mimic natural peptides with improved stability.

Basic Information

Item	Details
Product Name	2,6-Diazaspiro[4.5]Decane-2-Carboxylic Acid, 1,1-Dimethylethyl Ester
CAS No.	1086394-55-9
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	tert-Butyl 2,6-diazaspiro[4.5]decane-2-carboxylate; 2,6-Diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester; 2-(tert-Butoxycarbonyl)-2,6-diazaspiro[4.5]decane; Boc-2,6-diazaspiro[4.5]decane; 1,1-Dimethylethyl 2,6-diazaspiro[4.5]decane-2-carboxylate; 2-Boc-2,6-diazaspiro[4.5]decane; Spirocyclic Boc-protected diamine
EINECS	Contact for details

Quality Control

Every batch of 2,6-Diazaspiro[4.5]Decane-2-Carboxylic Acid, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP standards for advanced pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.