Description

2-((1-(tert-Butoxycarbonyl)Piperidin-4-Yl)Oxy)Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate featuring a nicotinic acid scaffold linked to a Boc-protected piperidine moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing small molecule therapeutics, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and preclinical drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Protease Inhibitor Development: Serves as a precursor or core structure in the design of protease inhibitors due to its specific molecular architecture.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Item	Detail
Product Name	2-((1-(tert-Butoxycarbonyl)Piperidin-4-Yl)Oxy)Nicotinic Acid
CAS No.	1086392-92-8
Molecular Formula	C16H22N2O5
Molecular Weight	322.36 g/mol
Synonyms	2-[(1-{[(tert-Butoxy)carbonyl]amino}-4-piperidinyl)oxy]pyridine-3-carboxylic acid; 2-((1-Boc-piperidin-4-yl)oxy)nicotinic acid; 2-[(1-Boc-4-piperidyl)oxy]nicotinic acid; 3-Pyridinecarboxylic acid, 2-[(1-[[(1,1-dimethylethoxy)carbonyl]-4-piperidinyl]oxy]-; 1086392-92-8; Boc-Pip-O-Nicotinic Acid
EINECS	Contact for details

Quality Control

Our production of 2-((1-(tert-Butoxycarbonyl)Piperidin-4-Yl)Oxy)Nicotinic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods such as HPLC, NMR, and MS. We support compliance with cGMP and ISO 9001 standards where required for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.