Description

2-(Pyrrolidin-3-Yloxy)Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of neurology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates targeting specific biological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Serves as a core scaffold for constructing novel molecules with potential neurological or metabolic activity.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying enzyme function and receptor interactions in biological systems.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	2-(Pyrrolidin-3-Yloxy)Nicotinic Acid
CAS No.	1086392-86-0
Molecular Formula	C10H12N2O3
Molecular Weight	208.22 g/mol
Synonyms	2-[(3-Pyrrolidinyl)oxy]-3-pyridinecarboxylic acid; Nicotinic acid, 2-(3-pyrrolidinyloxy)-; 2-(3-Pyrrolidinyloxy)nicotinic acid; 2-(Pyrrolidin-3-yloxy)pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(Pyrrolidin-3-Yloxy)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.