Description

2-(Pyrrolidin-3-Yloxy)-Nicotinonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in areas requiring complex nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop novel bioactive molecules.
• Chemical Biology Probes: Serves as a precursor for creating specialized probes to study enzyme function and biological pathways.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to construct complex heterocyclic frameworks for advanced material and agrochemical research.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	2-(Pyrrolidin-3-Yloxy)-Nicotinonitrile
CAS No.	1086392-84-8
Molecular Formula	C10H11N3O
Molecular Weight	189.21 g/mol
Synonyms	2-[(3-Pyrrolidinyl)oxy]-3-pyridinecarbonitrile; Nicotinonitrile, 2-(3-pyrrolidinyloxy)-; 3-Pyridinecarbonitrile, 2-[(3-pyrrolidinyl)oxy]-; 2-(3-Pyrrolidinyloxy)nicotinonitrile; 2-(Pyrrolidin-3-yloxy)nicotinonitrile; 1086392-84-8; 2-(Pyrrolidin-3-yloxy)pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-(Pyrrolidin-3-Yloxy)-Nicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.