Description

2-Bromo-4-Cyclopropylpyridine is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals, enabling critical structural modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create advanced fungicides and herbicides with the cyclopropyl moiety enhancing biological activity.
• Ligand & Catalyst Development: Serves as a building block for synthesizing specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Functional Group Transformation: Used in medicinal chemistry for further functionalization to introduce amines, ethers, or other heterocycles.

Basic Information

Product Name	2-Bromo-4-Cyclopropylpyridine
CAS No.	1086381-39-6
Molecular Formula	C8H8BrN
Molecular Weight	198.06 g/mol
Synonyms	4-Cyclopropyl-2-bromopyridine; 2-Bromo-4-cyclopropylpyridine; Pyridine, 2-bromo-4-cyclopropyl-; 2-Bromo-4-(cyclopropyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Cyclopropylpyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support customer audits and can supply material to meet specific regulatory or internal quality standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.