Description

2-Bromo-4-tert-Butoxypyridine is a high-purity, versatile brominated pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a tert-butoxy group, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as catalyst ligand synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its reactive bromine site for further functionalization.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of functionalized organic materials and liquid crystals, leveraging the pyridine core and alkoxy group.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis and Scale-Up: A valuable starting material for contract research organizations (CROs) and CDMOs performing custom synthesis from milligram to kilogram scale.

Basic Information

Product Name	2-Bromo-4-tert-Butoxypyridine
CAS No.	1086381-34-1
Molecular Formula	C9H12BrNO
Molecular Weight	230.10 g/mol
Synonyms	4-(tert-Butoxy)-2-bromopyridine; 2-Bromo-4-(tert-butoxy)pyridine; Pyridine, 2-bromo-4-(1,1-dimethylethoxy)-; 2-Bromo-4-(1,1-dimethylethoxy)pyridine; 2-Bromo-4-tert-butoxypyridine; 4-tert-Butoxy-2-bromopyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-tert-Butoxypyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment. We support compliance with relevant regulatory frameworks for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere if necessary to maintain purity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.