Description

4-Bromo-2-(cyclopropyl)pyridine is a versatile brominated pyridine derivative featuring a cyclopropyl substituent, serving as a critical building block in modern synthetic chemistry. Its unique structure makes it an invaluable intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its role in cross-coupling reactions and as a scaffold for functionalization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the pyridine core for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Research: Employed in academic and industrial R&D for method development in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Ligand Preparation: Useful for synthesizing specialized ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	4-Bromo-2-(cyclopropyl)pyridine
CAS No.	1086381-28-3
Molecular Formula	C8H8BrN
Molecular Weight	198.06 g/mol
Synonyms	2-Cyclopropyl-4-bromopyridine; 4-Bromo-2-cyclopropylpyridine; Pyridine, 4-bromo-2-cyclopropyl-; 1086381-28-3; 4-Bromo-2-(cyclopropyl)pyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(cyclopropyl)pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.