Description

6-(Piperidin-4-Yloxy)Nicotinic Acid is a high-purity organic building block featuring a nicotinic acid core linked to a piperidine moiety via an ether bridge. This compound matters as a versatile and critical intermediate in modern pharmaceutical research and development, enabling the synthesis of complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of potential drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Chemical Biology Probe Development: Used to create tool compounds for studying enzyme function and biological pathways due to its modifiable carboxylic acid and amine groups.
• Agrochemical Research: Serves as a building block for developing new active ingredients in crop protection and pest control formulations.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions in fine chemical synthesis.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for exploratory chemistry and method development projects.

Basic Information

Product Name	6-(Piperidin-4-Yloxy)Nicotinic Acid
CAS No.	1086379-90-9
Molecular Formula	C11H14N2O3
Molecular Weight	222.24 g/mol
Synonyms	6-[(4-Piperidinyl)oxy]-3-pyridinecarboxylic acid; 6-(Piperidin-4-yloxy)pyridine-3-carboxylic acid; 6-(4-Piperidyloxy)nicotinic acid; 3-Pyridinecarboxylic acid, 6-(4-piperidinyloxy)-; 1086379-90-9; 6-Piperidin-4-yloxy-nicotinic acid; 6-(1-Piperidinyloxy)nicotinic acid (isomer); Nicotinic acid, 6-(4-piperidyloxy)-
EINECS	Contact for details

Quality Control

Our 6-(Piperidin-4-Yloxy)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full batch traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.