Description

[6-(Tetrahydro-2H-Pyran-4-Yloxy)Pyridin-3-Yl]Methylamine is a high-purity, advanced pharmaceutical intermediate featuring a pyridine core substituted with a tetrahydro-2H-pyran-4-yloxy group and a methylamine moiety. This compound is of significant value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new molecular entities.
• API Synthesis: Serves as a crucial building block in the production of complex Active Pharmaceutical Ingredients (APIs), especially those containing functionalized pyridine scaffolds.
• Chemical Biology Probes: Utilized in the development of specialized probes and tool compounds for biochemical and cellular target validation.
• Custom Synthesis: Employed by fine chemical suppliers for bespoke manufacturing and contract synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	[6-(Tetrahydro-2H-Pyran-4-Yloxy)Pyridin-3-Yl]Methylamine
CAS No.	1086379-41-0
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	(6-((Tetrahydro-2H-pyran-4-yl)oxy)pyridin-3-yl)methanamine; 3-Pyridinemethanamine, 6-[(tetrahydro-2H-pyran-4-yl)oxy]-; 6-(Oxan-4-yloxy)pyridin-3-ylmethanamine; 6-(Tetrahydro-2H-pyran-4-yloxy)-3-pyridylmethylamine; 6-(Tetrahydro-2H-pyran-4-yloxy)nicotinylamine; 1086379-41-0; (6-(Tetrahydro-2H-pyran-4-yloxy)pyridin-3-yl)methylamine
EINECS	Contact for details

Quality Control

Our [6-(Tetrahydro-2H-Pyran-4-Yloxy)Pyridin-3-Yl]Methylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.