Description

4-(3-(Trifluoromethyl)Pyridin-2-Yloxy)Benzenamine is a high-value trifluoromethylpyridine derivative and an important organic synthetic intermediate. Its molecular structure, featuring a trifluoromethyl group and an aniline moiety, makes it a critical building block for advanced chemical synthesis, offering unique electronic and steric properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients. CAS No. 1086378-47-3.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a core building block for developing new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Used in the development of advanced organic electronic materials, including ligands for catalysts and components for organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring novel heterocyclic chemistry, fluorination reactions, and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Useful for creating specialized ligands used in transition metal catalysis for cross-coupling and other synthetic transformations.

Basic Information

Product Name	4-(3-(Trifluoromethyl)Pyridin-2-Yloxy)Benzenamine
CAS No.	1086378-47-3
Molecular Formula	C₁₂H₉F₃N₂O
Molecular Weight	254.21 g/mol
Synonyms	2-[(4-Aminophenoxy)methyl]-3-(trifluoromethyl)pyridine; 4-[[3-(Trifluoromethyl)-2-pyridinyl]oxy]benzenamine; 4-(3-Trifluoromethyl-pyridin-2-yloxy)-phenylamine; 2-(4-Aminophenoxy)-3-(trifluoromethyl)pyridine; Benzenamine, 4-[[3-(trifluoromethyl)-2-pyridinyl]oxy]-; 4-(3-(Trifluoromethyl)pyridin-2-yloxy)aniline
EINECS	Contact for details

Quality Control

Our 4-(3-(Trifluoromethyl)Pyridin-2-Yloxy)Benzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.