Description

(4-{[3-(Trifluoromethyl)Pyridin-2-Yl]Oxy}Phenyl)Methanol is a high-value trifluoromethylpyridine derivative, a key building block in modern synthetic chemistry. Its molecular structure, featuring a trifluoromethyl group and a benzylic alcohol, makes it a versatile intermediate for creating advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel compounds with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, leveraging the trifluoromethyl group for improved metabolic stability and lipophilicity.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers where the specific fluorinated aromatic system imparts desired electronic and physical characteristics.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(4-{[3-(Trifluoromethyl)Pyridin-2-Yl]Oxy}Phenyl)Methanol
CAS No.	1086376-57-9
Molecular Formula	C13H10F3NO2
Molecular Weight	269.22 g/mol
Synonyms	2-[(4-(Hydroxymethyl)phenoxy]-3-(trifluoromethyl)pyridine; [4-[[3-(Trifluoromethyl)-2-pyridinyl]oxy]phenyl]methanol; 4-((3-(Trifluoromethyl)pyridin-2-yl)oxy)benzyl alcohol; (4-((3-(Trifluoromethyl)pyridin-2-yl)oxy)phenyl)methanol; CAS 1086376-57-9; 2-Pyridinemethanol, α-[4-[[3-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]-; 3-Trifluoromethyl-2-(4-hydroxymethylphenoxy)pyridine
EINECS	Contact for details

Quality Control

Our production of (4-{[3-(Trifluoromethyl)Pyridin-2-Yl]Oxy}Phenyl)Methanol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets exacting customer specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment, and we support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as an easily oxidized compound, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.