Description

n-(5-Bromo-2-Methoxypyridin-3-Yl)-2,4-Difluorobenzenesulfonamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, particularly in the development of targeted small-molecule therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a standard reference material for scaling up synthetic routes from laboratory to pilot plant scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for investigating new organic reactions and heterocyclic compound synthesis.

Basic Information

Product Name	n-(5-Bromo-2-Methoxypyridin-3-Yl)-2,4-Difluorobenzenesulfonamide
CAS No.	1086063-46-8
Molecular Formula	C12H9BrF2N2O3S
Molecular Weight	379.18 g/mol
Synonyms	5-Bromo-2-methoxy-N-(2,4-difluorophenylsulfonyl)pyridin-3-amine; 2,4-Difluoro-N-(5-bromo-2-methoxypyridin-3-yl)benzenesulfonamide; 1086063-46-8; 3-Pyridinamine, 5-bromo-2-methoxy-N-[(2,4-difluorophenyl)sulfonyl]-; Benzenesulfonamide, 2,4-difluoro-N-(5-bromo-2-methoxy-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our n-(5-Bromo-2-Methoxypyridin-3-Yl)-2,4-Difluorobenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.