Description

(R)-tert-Butyl 1-(5-Nitropyridine-2-Yl)Pyrrolidine-3-Ylcarbamate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is of significant value for its role in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry and drug discovery. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, where precise stereochemistry and reliable quality are critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Asymmetric Synthesis: Serves as a building block for constructing complex molecules with defined stereocenters.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing outsourced R&D and production services.

Basic Information

Product Name	(R)-tert-Butyl 1-(5-Nitropyridine-2-Yl)Pyrrolidine-3-Ylcarbamate
CAS No.	1085841-16-2
Molecular Formula	C14H20N4O4
Molecular Weight	308.33 g/mol
Synonyms	(R)-tert-Butyl 1-(5-nitropyridin-2-yl)pyrrolidine-3-ylcarbamate; tert-Butyl N-[(3R)-1-(5-nitropyridin-2-yl)pyrrolidin-3-yl]carbamate; (R)-1-(5-Nitropyridin-2-yl)pyrrolidine-3-yl tert-butylcarbamate; (R)-N-Boc-1-(5-nitropyridin-2-yl)pyrrolidin-3-amine; (R)-tert-Butyl (1-(5-nitropyridin-2-yl)pyrrolidin-3-yl)carbamate; (R)-3-((tert-Butoxycarbonyl)amino)-1-(5-nitropyridin-2-yl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 1-(5-Nitropyridine-2-Yl)Pyrrolidine-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.