Description

Methyl 4-Bromo-5-Fluoro-2-Methoxybenzoate is a high-purity fluorinated and brominated aromatic ester, serving as a critical advanced intermediate in modern organic synthesis. Its unique halogenated structure makes it an invaluable building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the bromo-fluoro substitution pattern can enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as semiconductors and liquid crystals, where halogenated aromatics tune electronic properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 4-Bromo-5-Fluoro-2-Methoxybenzoate
CAS No.	1084953-18-3
Molecular Formula	C9H8BrFO3
Molecular Weight	263.06 g/mol
Synonyms	4-Bromo-5-fluoro-2-methoxybenzoic acid methyl ester; Methyl 4-bromo-5-fluoro-2-methoxybenzoate; Benzoic acid, 4-bromo-5-fluoro-2-methoxy-, methyl ester; 2-Methoxy-4-bromo-5-fluorobenzoic acid methyl ester; Methyl 4-bromo-5-fluoro-o-anisate; 1084953-18-3; SCHEMBL23802227
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-5-Fluoro-2-Methoxybenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.