Description

(2S,3S,4Ar,8R,8Ar)-Octahydro-2,3-Dimethoxy-2,3-Dimethyl-1,4-Dioxino[2,3-C]Pyridine-8-Methanol is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. Its complex fused-ring structure containing a dioxino-pyridine core and a pendant methanol group makes it a valuable chiral intermediate for constructing sophisticated molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the construction of complex, bioactive molecules for next-generation pesticides and herbicides, leveraging its stereochemical complexity.
• Asymmetric Catalysis Ligand Precursor: The defined stereocenters and heteroatom-rich structure make it a potential precursor for novel chiral ligands and organocatalysts.
• Chemical Biology Probe Development: Employed in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale production of fine chemicals requiring its specific stereochemistry.

Basic Information

Product Name	(2S,3S,4Ar,8R,8Ar)-Octahydro-2,3-Dimethoxy-2,3-Dimethyl-1,4-Dioxino[2,3-C]Pyridine-8-Methanol
CAS No.	1084896-52-5
Molecular Formula	C13H23NO5
Molecular Weight	273.33 g/mol
Synonyms	1,4-Dioxino[2,3-c]pyridine-8-methanol, octahydro-2,3-dimethoxy-2,3-dimethyl-, (2S,3S,4aR,8R,8aR)-; (2S,3S,4aR,8R,8aR)-Octahydro-2,3-dimethoxy-2,3-dimethyl-1,4-dioxino[2,3-c]pyridine-8-methanol; 8-Methanol Derivative of Octahydrodimethoxydimethyldioxinopyridine; Chiral Dioxinopyridine Methanol Derivative; CAS 1084896-52-5
EINECS	Contact for details

Quality Control

Every batch of (2S,3S,4Ar,8R,8Ar)-Octahydro-2,3-Dimethoxy-2,3-Dimethyl-1,4-Dioxino[2,3-C]Pyridine-8-Methanol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.