Description

6-(1H-Imidazol-1-yl)pyridine-2-carboxylic acid is a high-value heterocyclic building block featuring a fused pyridine-imidazole core structure. This compound is essential for medicinal chemistry research and development, serving as a key precursor for synthesizing novel small molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing kinase inhibitors and other targeted drug candidates.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of kinase inhibitors and other biologically active molecules in drug discovery pipelines.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries via parallel synthesis and structure-activity relationship (SAR) studies.
• Bioconjugation & Probe Development: The carboxylic acid moiety allows for conjugation to other molecules, useful in creating chemical probes for biological target identification.
• Ligand Synthesis for Catalysis: Can be employed in the preparation of specialized ligands for transition metal catalysis in asymmetric synthesis.
• Agrochemical Research: Serves as a building block in the development of new active ingredients for crop protection products.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or metal-organic frameworks (MOFs) due to its chelating ability.

Basic Information

Product Name	6-(1H-Imidazol-1-yl)pyridine-2-carboxylic Acid
CAS No.	1083402-25-8
Molecular Formula	C9H7N3O2
Molecular Weight	189.17 g/mol
Synonyms	6-(1H-Imidazol-1-yl)picolinic acid; 2-Pyridinecarboxylic acid, 6-(1H-imidazol-1-yl)-; 6-(Imidazol-1-yl)pyridine-2-carboxylic acid; 1-(6-Carboxypyridin-2-yl)-1H-imidazole; 6-(1H-Imidazol-1-yl)-2-pyridinecarboxylic acid; 2-Carboxy-6-(imidazol-1-yl)pyridine; 6-Imidazol-1-yl-pyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-(1H-Imidazol-1-yl)pyridine-2-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.