Description

Methyl 6-Nitro-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate CAS NO 1083196-32-0 is a high-purity, advanced pharmaceutical intermediate characterized by its nitro-substituted pyrrolopyridine core structure. This compound is of significant value for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and targeted drug discovery programs.

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities with potential therapeutic benefits.
• Agrochemical Development: Serves as a starting material for creating new active ingredients in crop protection research.
• Organic Synthesis & Process Chemistry: Employed in academic and industrial laboratories for developing new synthetic methodologies and scaling up complex heterocyclic compound production.
• Bioconjugate & Probe Synthesis: The reactive ester group makes it suitable for creating fluorescent probes or bioconjugates for biochemical and diagnostic applications.

Basic Information

Product Name	Methyl 6-Nitro-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate
CAS No.	1083196-32-0
Molecular Formula	C9H7N3O4
Molecular Weight	221.17 g/mol
Synonyms	Methyl 6-nitro-1H-pyrrolo[3,2-b]pyridine-2-carboxylate; 1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid, 6-nitro-, methyl ester; 6-Nitro-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid methyl ester; Methyl 6-nitropyrrolo[3,2-b]pyridine-2-carboxylate; 1083196-32-0; Methyl 6-nitro-pyrrolo[3,2-b]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 6-Nitro-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.