Description

6-(Thien-2-Yl)-4-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers developing new therapeutic agents and high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Employed in the research and synthesis of new generation pesticides and herbicides due to its bioactive heterocyclic core.
• Organic Electronic Materials: Investigated as a potential building block for organic semiconductors and light-emitting materials, leveraging the thiophene and pyridine motifs.
• Chemical Biology Probes: Utilized in the development of molecular probes and inhibitors for studying enzyme function and biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	6-(Thien-2-Yl)-4-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid
CAS No.	1083196-28-4
Molecular Formula	C13H7F3N2O2S
Molecular Weight	312.27 g/mol
Synonyms	6-(Thiophen-2-yl)-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 6-(2-thienyl)-4-(trifluoromethyl)-; 1083196-28-4; 6-(Thien-2-yl)-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 6-(2-Thienyl)-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 4-Trifluoromethyl-6-thiophen-2-yl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-(Thien-2-Yl)-4-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical parameters such as assay purity and impurity profiles. Our quality system is designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored away from direct light exposure. Keep the container tightly sealed when not in use to protect from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.