Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 5-Chloro-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with specific modes of action.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 5-Chloro-, Ethyl Ester
CAS No.	1083181-28-5
Molecular Formula	C10H9ClN2O2
Molecular Weight	224.64 g/mol
Synonyms	Ethyl 5-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 5-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-, ethyl ester; 1083181-28-5; 5-Chloro-ethyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; Ethyl 5-chloro-7-azaindole-2-carboxylate; 5-Chloro-7-azaindole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 5-Chloro-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We support development and commercial projects with material that meets stringent in-house specifications aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.