Description

Ethyl 6-Chloro-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This heterocyclic compound serves as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex fused pyrazolopyridine scaffolds.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and functional materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for clients.

Basic Information

Product Name	Ethyl 6-Chloro-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylate
CAS No.	1083181-27-4
Molecular Formula	C9H8ClN3O2
Molecular Weight	225.63 g/mol
Synonyms	6-Chloro-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid ethyl ester; Ethyl 6-chloro-1H-pyrazolo[3,4-b]pyridine-3-carboxylate; 1H-Pyrazolo[3,4-b]pyridine-3-carboxylic acid, 6-chloro-, ethyl ester; 1083181-27-4; Ethyl 6-chloro-1H-pyrazolo[3,4-b]pyridine-3-carboxylate; 6-Chloro-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Chloro-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specified parameters. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.