Description

2-Bromo-1H-Pyrrolo[2,3-B]Pyridine is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological systems.
• Cross-Coupling Reactions: Acts as a competent substrate in Suzuki, Stille, and Buchwald-Hartwig amination reactions to form new carbon-carbon and carbon-nitrogen bonds.
• Library Synthesis: Utilized in combinatorial and parallel synthesis for generating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	2-Bromo-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1083181-25-2
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	2-Bromo-1H-pyrrolo[2,3-b]pyridine; 2-Bromo-7-azaindole; 2-Bromo-1H-pyrrolo[2,3-b]pyridine; 2-Bromo-1H-pyrrolo[2,3-b]pyridin; 2-Bromo-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 2-bromo-; 2-Bromo-1H-7-azaindole
EINECS	Contact for details

Quality Control

Our 2-Bromo-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity building blocks for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.