Description

1-Benzenesulfonyl-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid Methyl Ester is a high-purity, functionalized heterocyclic building block designed for advanced pharmaceutical and agrochemical research. This compound is a critical intermediate in the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry and drug discovery programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and develop new drug candidates.
• Agrochemical Development: Acts as a precursor in the creation of new crop protection agents and herbicides.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds on a commercial scale.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	1-Benzenesulfonyl-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid Methyl Ester
CAS No.	1083181-12-7
Molecular Formula	C15H12N2O4S
Molecular Weight	316.33 g/mol
Synonyms	Methyl 1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 1-(phenylsulfonyl)-, methyl ester; 1-Benzenesulfonyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester; Methyl 1-benzenesulfonyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylate; 1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1-Benzenesulfonyl-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.