Description

3-(6-Amino-3-Methyl-Pyridin-2-Yl)-Benzoicacidtert-Butylester is a high-purity, advanced pharmaceutical intermediate featuring a unique pyridine-benzoate hybrid structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise molecular architecture is required for target specificity and efficacy. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for commercial API manufacturing under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for investigating new organic reactions and catalytic processes.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals for various industrial applications.

Basic Information

Product Name	3-(6-Amino-3-Methyl-Pyridin-2-Yl)-Benzoicacidtert-Butylester
CAS No.	1083057-14-0
Molecular Formula	C17H20N2O2
Molecular Weight	284.35 g/mol
Synonyms	tert-Butyl 3-(6-amino-3-methylpyridin-2-yl)benzoate; 3-(6-Amino-3-methyl-2-pyridinyl)benzoic acid 1,1-dimethylethyl ester; Benzoic acid, 3-(6-amino-3-methyl-2-pyridinyl)-, 1,1-dimethylethyl ester; 2-(3-(tert-Butoxycarbonyl)phenyl)-5-methylpyridin-3-amine; 1083057-14-0; 3-(6-Amino-3-methylpyridin-2-yl)benzoic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of 3-(6-Amino-3-Methyl-Pyridin-2-Yl)-Benzoicacidtert-Butylester adheres to stringent quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up work. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to verify identity, purity, and the absence of specified impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.