Description

3-(Chloromethyl)-1-Methanesulfonylpiperidine CAS NO 1082944-42-0 is a high-purity, functionalized piperidine derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and versatile building block in medicinal chemistry, enabling the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Synthesis: Intermediate in the production of advanced pesticides and herbicides requiring specific piperidine-based scaffolds.
• Chemical Biology Probes: Serves as a precursor for labeling reagents and molecular probes used in biochemical research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-(Chloromethyl)-1-Methanesulfonylpiperidine
CAS No.	1082944-42-0
Molecular Formula	C7H14ClNO2S
Molecular Weight	211.71 g/mol
Synonyms	1-(Methanesulfonyl)-3-(chloromethyl)piperidine; 3-(Chloromethyl)-1-(methylsulfonyl)piperidine; 1-Methanesulfonyl-3-chloromethylpiperidine; Piperidine, 3-(chloromethyl)-1-(methylsulfonyl)-; 1082944-42-0; 3-Chloromethyl-1-methanesulfonylpiperidine; 3-(Chloromethyl)-1-(methanesulfonyl)piperidine
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)-1-Methanesulfonylpiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request. We support development and commercial projects requiring material suitable for use under ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.