Description

5-(Piperazin-1-Yl)Pyridin-2-Amine CAS NO 1082876-26-3 is a high-purity, heterocyclic organic compound featuring a pyridine core substituted with an amine and a piperazine group. This specific molecular architecture makes it a versatile and critical building block (intermediate) in advanced organic synthesis. It is primarily utilized by pharmaceutical research and development organizations for the creation of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for central nervous system (CNS) agents, kinase inhibitors, and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the piperazine-pyridine scaffold can contribute to specific biological activity.
• Ligand for Catalysis: Serves as a precursor for designing novel ligands in transition metal catalysis, facilitating complex chemical transformations.
• Material Science Research: Employed in the synthesis of organic semiconductors, coordination polymers, or other functional materials due to its electron-donating and chelating properties.
• Chemical Biology Probe Development: Used as a core structure for creating molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	5-(Piperazin-1-Yl)Pyridin-2-Amine
CAS No.	1082876-26-3
Molecular Formula	C9H14N4
Molecular Weight	178.24 g/mol
Synonyms	2-Amino-5-(piperazin-1-yl)pyridine; 5-(1-Piperazinyl)-2-pyridinamine; 2-Pyridinamine, 5-(1-piperazinyl)-; 5-Piperazin-1-ylpyridin-2-amine; 1082876-26-3; 5-(Piperazin-1-yl)pyridin-2-amine; 2-Amino-5-piperazin-1-ylpyridine
EINECS	Contact for details

Quality Control

Our 5-(Piperazin-1-Yl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.