Description

2-Cyano-3-(3-Pyridyl)Propionic Acid is a versatile pyridine-based carboxylic acid derivative that serves as a critical advanced pharmaceutical intermediate and organic synthesis building block. Its unique molecular structure, featuring both a cyano and a carboxylic acid functional group on a propionic acid backbone attached to a pyridine ring, makes it a valuable precursor for constructing complex molecules. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Organic Electronic Materials: Investigated as a component in the synthesis of organic semiconductors and conductive polymers due to the electron-withdrawing cyano group.
• Peptidomimetics Research: The carboxylic acid and cyano groups make it a useful scaffold for designing peptide analogs and enzyme inhibitors.
• Academic and R&D Laboratories: Employed in methodological studies and as a starting material for complex organic transformations.

Basic Information

Product Name	2-Cyano-3-(3-Pyridyl)Propionic Acid
CAS No.	1082386-59-1
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	3-(3-Pyridyl)-2-cyanopropanoic Acid; 2-Cyano-3-(pyridin-3-yl)propanoic Acid; 3-Pyridinepropanoic acid, 2-cyano-; (2-Cyano-3-pyridin-3-yl-propyl)-phosphonic acid diethyl ester (precursor); β-Cyano-β-(3-pyridyl)propionic Acid
EINECS	Contact for details

Quality Control

Our 2-Cyano-3-(3-Pyridyl)Propionic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.