Description

3-o-Tolyl-[1,2,4]Triazolo[4,3-A]Pyridine-8-Carboxylic Acid is a high-purity heterocyclic carboxylic acid derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who are developing next-generation small molecule drugs and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Fine Chemical Synthesis: Serves as a precursor for complex organic molecules used in material science and specialty chemistry applications.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	3-o-Tolyl-[1,2,4]Triazolo[4,3-A]Pyridine-8-Carboxylic Acid
CAS No.	1082143-81-4
Molecular Formula	C15H11N3O2
Molecular Weight	265.27 g/mol
Synonyms	3-(2-Methylphenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxylic acid; 3-(o-Tolyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxylic acid; 3-(2-Methylphenyl)-1,2,4-triazolo[4,3-a]pyridine-8-carboxylic acid; 1082143-81-4; 3-o-Tolyl-1,2,4-triazolo[4,3-a]pyridine-8-carboxylic acid; Triazolopyridine carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 3-o-Tolyl-[1,2,4]Triazolo[4,3-A]Pyridine-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.