Description

S-4-Chlorophenylglycine Methyl Ester Hydrochloride is a high-purity chiral intermediate essential for the synthesis of active pharmaceutical ingredients (APIs). This compound matters as a critical building block for developing enantiomerically pure pharmaceuticals, ensuring the efficacy and safety of the final drug product. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel APIs, particularly for central nervous system (CNS) and cardiovascular drugs.
• Peptide Synthesis: Used in the preparation of modified amino acids and peptide analogs for drug discovery programs.
• Asymmetric Synthesis: Serves as a precursor for chiral catalysts or auxiliaries in stereoselective chemical transformations.
• Agrochemical Research: Employed in the development of enantiomerically pure herbicides and pesticides.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the synthesis of complex organic molecules.

Basic Information

Product Name	S-4-Chlorophenylglycine Methyl Ester Hydrochloride
CAS No.	1081766-09-7
Molecular Formula	C9H11Cl2NO2
Molecular Weight	236.10 g/mol
Synonyms	(S)-Methyl 2-amino-2-(4-chlorophenyl)acetate hydrochloride; (S)-4-Chlorophenylglycine methyl ester HCl; L-4-Chlorophenylglycine methyl ester hydrochloride; Methyl (S)-2-amino-2-(4-chlorophenyl)acetate hydrochloride; (S)-α-Amino-4-chlorobenzeneacetic acid methyl ester hydrochloride; (S)-Methyl 2-amino-(4-chlorophenyl)acetate hydrochloride; (S)-MeO2C-CH(NH2)-C6H4-4-Cl · HCl
EINECS	Contact for details

Quality Control

Our S-4-Chlorophenylglycine Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure compliance with high-purity standards typical for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.