Description

n-(2-Chloropyridin-4-Yl)-3-{4-Methyl-7-[(2-Methylprop-2-En-1-Yl)Oxy]-2-Oxo-2H-Chromen-6-Yl}Propanamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of targeted small molecule drugs. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for oncology and other targeted therapies.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for complex final drug substances.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor binding assays due to its specific molecular scaffold.
• Fine Chemical Production: Used by contract development and manufacturing organizations (CDMOs) for custom synthesis projects.

Basic Information

Product Name	n-(2-Chloropyridin-4-Yl)-3-{4-Methyl-7-[(2-Methylprop-2-En-1-Yl)Oxy]-2-Oxo-2H-Chromen-6-Yl}Propanamide
CAS No.	1081134-48-6
Molecular Formula	C22H21ClN2O4
Molecular Weight	412.87 g/mol
Synonyms	3-[4-Methyl-7-[(2-methylprop-2-en-1-yl)oxy]-2-oxo-2H-chromen-6-yl]-N-(2-chloropyridin-4-yl)propanamide; 6-[3-[(2-Chloro-4-pyridinyl)amino]-3-oxopropyl]-4-methyl-7-[(2-methyl-2-propen-1-yl)oxy]-2H-1-benzopyran-2-one; Propanamide, N-(2-chloro-4-pyridinyl)-3-[4-methyl-7-[(2-methyl-2-propen-1-yl)oxy]-2-oxo-2H-1-benzopyran-6-yl]-; CAS 1081134-48-6
EINECS	Contact for details

Quality Control

Our n-(2-Chloropyridin-4-Yl)-3-{4-Methyl-7-[(2-Methylprop-2-En-1-Yl)Oxy]-2-Oxo-2H-Chromen-6-Yl}Propanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.