Description

2-Phenyl-6-Pyridin-3-Yl-1,2-Dihydro-3H-Pyrazolo[3,4-B]Pyridin-3-One is a high-purity, complex heterocyclic compound that serves as a critical building block in advanced pharmaceutical research and development. This compound is valued for its unique molecular scaffold, which is instrumental in the design and synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for projects targeting kinase inhibition and other therapeutic areas. Our supply ensures consistent quality and reliable availability for your most demanding synthesis workflows.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Its structural features make it a valuable intermediate for synthesizing potential kinase inhibitors, a major class of targeted therapeutics.
• Chemical Biology Probes: Employed in the creation of molecular probes to study biological pathways and protein functions in academic and industrial research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity heterocyclic chemistry.

Basic Information

Product Name	2-Phenyl-6-Pyridin-3-Yl-1,2-Dihydro-3H-Pyrazolo[3,4-B]Pyridin-3-One
CAS No.	1081130-33-7
Molecular Formula	C₁₇H₁₂N₄O
Molecular Weight	288.31 g/mol
Synonyms	3H-Pyrazolo[3,4-b]pyridin-3-one, 1,2-dihydro-2-phenyl-6-(3-pyridinyl)-; 2-Phenyl-6-(pyridin-3-yl)-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-one; 1081130-33-7; 6-(3-Pyridyl)-2-phenyl-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-one; Pyrazolopyridinone derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Phenyl-6-Pyridin-3-Yl-1,2-Dihydro-3H-Pyrazolo[3,4-B]Pyridin-3-One is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support your regulatory and research requirements. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed HPLC purity, identity confirmation, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.