Description

2-(2-(2-Fluorophenyl)-5-Hydroxy-8-Methyl-7-Oxo-7,8-Dihydropy CAS NO 1080644-24-1 is a high-purity fluorinated heterocyclic compound, serving as a critical advanced pharmaceutical intermediate (API intermediate) for research and development. Its value lies in its precise molecular structure, which is essential for synthesizing novel active pharmaceutical ingredients with targeted therapeutic effects. This compound is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers developing next-generation drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry for lead optimization and the creation of new chemical entities (NCEs).
• Oncology Research: Serves as a precursor for potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Synthesis: Employed in the development of compounds targeting neurological and psychiatric disorders.
• Preclinical & Clinical Trial Material: Supplied for the production of materials required for non-clinical and clinical studies.
• Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying fluorinated heterocycle chemistry and bioactivity.

Basic Information

Item	Detail
Product Name	2-(2-(2-Fluorophenyl)-5-Hydroxy-8-Methyl-7-Oxo-7,8-Dihydropy CAS NO 1080644-24-1
CAS No.	1080644-24-1
Molecular Formula	C12H10FNO3
Molecular Weight	235.21 g/mol
Synonyms	2-(2-(2-Fluorophenyl)-5-hydroxy-8-methyl-7-oxo-7,8-dihydropyridin-1-ium; 1H-Pyridin-1-ium, 2-[2-(2-fluorophenyl)-5-hydroxy-8-methyl-7-oxo-7,8-dihydro-; 1080644-24-1; 2-(2-Fluorophenyl)-5-hydroxy-8-methyl-7-oxo-7,8-dihydro-1H-pyridin-1-ium; Fluorinated dihydropyridine derivative; API Intermediate 1080644-24-1
EINECS	Contact for details

Quality Control

Our 2-(2-(2-Fluorophenyl)-5-Hydroxy-8-Methyl-7-Oxo-7,8-Dihydropy CAS NO 1080644-24-1 is manufactured under strict quality management systems. Products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.