Description

5-Methyl-2-Trifluoromethyl-Nicotinic Acid Ethyl Ester is a high-value trifluoromethylated pyridine derivative, a key building block in modern synthetic chemistry. Its core value lies in the trifluoromethyl group, which significantly enhances the metabolic stability, lipophilicity, and bioavailability of target molecules. This compound is primarily sought after by pharmaceutical and agrochemical R&D departments for the synthesis of novel active ingredients, including potential drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial synthon for constructing complex molecules in medicinal chemistry, particularly for developing active pharmaceutical ingredients (APIs) with improved pharmacokinetic profiles.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to enhanced efficacy and environmental stability.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences industry.

Basic Information

Product Name	5-Methyl-2-Trifluoromethyl-Nicotinic Acid Ethyl Ester
CAS No.	1079249-90-3
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	Ethyl 5-Methyl-2-(trifluoromethyl)nicotinate; Ethyl 5-Methyl-2-(trifluoromethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-methyl-2-(trifluoromethyl)-, ethyl ester; 5-Methyl-2-trifluoromethylnicotinic acid ethyl ester; 2-Trifluoromethyl-5-methylnicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-Trifluoromethyl-Nicotinic Acid Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is supplied with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.