Description

2-Chloro-3-Fluoro-5-Nitropyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated and nitrated pyridine structure makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by material scientists exploring functional dyes and electronic chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antibacterial research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogen and nitro groups for bioactivity.
• Material Science Precursor: Serves as a building block for functional materials, including liquid crystals, organic light-emitting diodes (OLEDs), and conductive polymers.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring novel heterocyclic chemistry, cross-coupling reactions, and nucleophilic substitution pathways.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments due to the electron-withdrawing nitro group which influences color properties.
• Ligand and Catalyst Development: Acts as a precursor for creating novel ligands used in catalytic systems for asymmetric synthesis.

Basic Information

Product Name	2-Chloro-3-Fluoro-5-Nitropyridine
CAS No.	1079179-12-6
Molecular Formula	C5H2ClFN2O2
Molecular Weight	176.53 g/mol
Synonyms	5-Nitro-2-chloro-3-fluoropyridine; 2-Chloro-3-fluoro-5-nitropyridine; 3-Fluoro-2-chloro-5-nitropyridine; Pyridine, 2-chloro-3-fluoro-5-nitro-; 1079179-12-6; 2-Chloro-3-fluoropyridine-5-nitropyridine; 5-Nitro-3-fluoro-2-chloropyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluoro-5-Nitropyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO-guided environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.