Description

5-Amino-6-Iodo-Pyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block featuring distinct amino, cyano, and iodo substituents. This compound matters for its unique reactivity profile, enabling precise synthetic modifications critical for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

This versatile chemical intermediate serves as a key precursor in various sophisticated synthetic pathways.

• Pharmaceutical Intermediate: Core building block for the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other heterocyclic-based therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials and advanced polymers.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce complex fragments.
• Functional Group Transformation: The amino and cyano groups allow for further derivatization to amides, amidines, and heterocyclic ring systems.

Basic Information

Item	Details
Product Name	5-Amino-6-Iodo-Pyridine-2-Carbonitrile
CAS No.	1079054-78-6
Molecular Formula	C6H4IN3
Molecular Weight	245.02 g/mol
Synonyms	6-Iodo-5-aminopyridine-2-carbonitrile; 2-Cyano-5-amino-6-iodopyridine; 5-Amino-6-iodo-2-cyanopyridine; 6-Iodo-2-cyanopyridin-5-amine; 5-Amino-6-iodopicolinonitrile; (6-Iodo-5-aminopyridin-2-yl)methanenitrile; 2-Pyridinecarbonitrile, 5-amino-6-iodo-
EINECS	Contact for details

Quality Control

Our 5-Amino-6-Iodo-Pyridine-2-Carbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued lighting where practical.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.