Description

Ethyl 5-(tert-Butoxycarbonylamino)Picolinate is a high-purity, protected amino acid derivative and a key pharmaceutical intermediate. This compound is specifically engineered for use in complex organic synthesis, particularly in the construction of peptide mimetics and active pharmaceutical ingredients (APIs). It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and production.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting protein-protein interactions.
• Peptidomimetic Synthesis: Used to incorporate modified amino acid structures into peptide chains to enhance metabolic stability and bioavailability.
• API Development: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Employed in the development of new pesticides and herbicides that require specific chiral or functionalized heterocyclic components.
• Ligand and Catalyst Design: Useful for creating specialized ligands for metal catalysis or molecular recognition applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	Ethyl 5-(tert-Butoxycarbonylamino)Picolinate
CAS No.	1078129-19-7
Molecular Formula	C13H18N2O4
Molecular Weight	266.29 g/mol
Synonyms	5-[(tert-Butoxycarbonyl)amino]pyridine-2-carboxylic acid ethyl ester; Ethyl 5-[(tert-butoxycarbonyl)amino]picolinate; Boc-5-Amino-picolinic acid ethyl ester; 2-Pyridinecarboxylic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-, ethyl ester; Ethyl 5-(Boc-amino)picolinate; 5-(N-Boc-amino)picolinic acid ethyl ester; Ethyl 5-((tert-butoxycarbonyl)amino)picolinate
EINECS	Contact for details

Quality Control

Our Ethyl 5-(tert-Butoxycarbonylamino)Picolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.