Description

Trimethyl (R)-2-Methylpropane-1,1,3-Tricarboxylate is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its well-defined stereochemistry and functional group array make it a critical precursor for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in the development of protease inhibitors, antiviral agents, and other therapeutics requiring specific stereocenters.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides where biological activity is highly stereospecific.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that demand high enantiomeric purity.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within university and industrial laboratories.
• Peptidomimetics: Useful in the design and synthesis of peptidomimetic compounds, which mimic peptides but with enhanced stability and bioavailability.

Basic Information

Item	Details
Product Name	Trimethyl (R)-2-Methylpropane-1,1,3-Tricarboxylate
CAS No.	1076218-98-8
Molecular Formula	C10H16O6
Molecular Weight	232.23 g/mol
Synonyms	(R)-2-Methyl-1,1,3-propanetricarboxylic acid trimethyl ester; (R)-Trimethyl 2-methyl-1,1,3-propanetricarboxylate; (R)-2-Methylpropane-1,1,3-tricarboxylic acid trimethyl ester; Methyl (R)-2-methyl-1,1,3-propanetricarboxylate; (R)-Methyl 2-methyl-1,1,3-propanetricarboxylate; (R)-1,1,3-Trimethoxycarbonyl-2-methylpropane
EINECS	Contact for details

Quality Control

Our Trimethyl (R)-2-Methylpropane-1,1,3-Tricarboxylate is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC/MS, to verify identity, purity, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.