Description

3-[(1,1-Dimethylethyl)Dimethylsilyloxy]-5-(1-Methylamino)-5-Oxopentanoic Acid is a high-purity, protected amino acid derivative designed for advanced synthetic chemistry. This compound is a critical building block for the synthesis of complex peptides and other biologically active molecules, offering precise control over molecular structure. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediates: Serves as a key synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for peptide-based drugs.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to construct specific peptide sequences.
• Proteomics Research: Employed in biochemical research for the study of protein structure, function, and interactions.
• Bioconjugation: Acts as a linker or functional handle for attaching peptides to other molecules, surfaces, or carriers in drug delivery system development.
• Chemical Biology Probes: Utilized in the creation of labeled or modified peptides for diagnostic assays and molecular imaging.
• Custom Synthesis: A valuable starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	3-[(1,1-Dimethylethyl)Dimethylsilyloxy]-5-(1-Methylamino)-5-Oxopentanoic Acid
CAS No.	1076199-66-0
Molecular Formula	C14H29NO4Si
Molecular Weight	303.47 g/mol
Synonyms	5-(Methylamino)-5-oxo-3-[(tert-butyldimethylsilyl)oxy]pentanoic Acid; 3-(tert-Butyldimethylsilyloxy)-5-(methylcarbamoyl)pentanoic Acid; N-Methyl-3-[(tert-butyldimethylsilyl)oxy]-5-carboxyvaleramide; TBDMS-protected Glutamic Acid Methylamide Derivative; tert-Butyldimethylsilyl 5-(Methylamino)-5-oxopentanoate; CAS 1076199-66-0
EINECS	Contact for details

Quality Control

Our production of 3-[(1,1-Dimethylethyl)Dimethylsilyloxy]-5-(1-Methylamino)-5-Oxopentanoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.